Home > Field of Cooperation > Health Research > Gut leak and microbiome contributions to severe dengue disease
Gut leak and microbiome contributions to severe dengue disease |
| Principal Investigator / Affiliation | Katryn Stacey (Professor) / The University of Queensland  Australia |
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Asada Leelahavanichkul (Associate Professor) / Chulalongkorn University  Thailand |
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Dieter Tourlousse (Senior scientist) / National Institute of Advanced Industrial Science and Technology  Japan |
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| Year Adopted | 2022 |
| Research Period | 3 years |
| General Description of the Research Project | This cooperative research project aims to establish the role of gut bacteria in the manifestations of severe dengue virus infection. Mosquito-borne dengue virus is a major health threat in the tropics, with severe disease involving life-threatening bleeding and shock. We propose that severe disease is the result of virus-induced damage to the gut, allowing bacterial products into the body. Collaborators in Thailand, Japan and Australia will investigate the impact of gut bacteria on dengue disease and possible live bacterial therapies |
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Researchers
| Principal Investigator / Country of Research Team | 
Katryn Stacey Australia
Asada Leelahavanichkul Thailand
Dieter Tourlousse Japan |
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