Home > Field of Cooperation > Health Research > Role of the pre-existing immunity to Japanese encephalitis and Zika viruses in influencing dengue disease outcome and vaccination program in Vietnam and Thailand
Role of the pre-existing immunity to Japanese encephalitis and Zika viruses in influencing dengue disease outcome and vaccination program in Vietnam and Thailand |
| Principal Investigator / Affiliation | Sujan Shresta (Associate Professor) / La Jolla Institute for Immunology  USA |
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Thi Quynh Mai Le (Vice Director) / National Institute of Hygiene and Epidemiology  Vietnam |
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Montarop Yamabhai (Director of Molecular Biotechnology) / Suranaree University of Technology  Thailand |
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| Year Adopted | 2020 |
| Research Period | 3 years |
| General Description of the Research Project | This cooperative research project aims to decipher whether cross-reactive immunity to Japanese encephalitis (JEV) and Zika (ZIKV) viruses modulates disease manifestations and viral genetic diversity during subsequent infection with dengue virus (DENV) in Vietnam and Thailand. In addition, this project seeks to identify novel broadly neutralizing antibodies against DENV, JEV, and ZIKV for the development of innovative diagnostics and therapeutics. |
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Researchers
| Principal Investigator / Country of Research Team | 
Sujan Shresta the United States
Thi Quynh Mai Le Vietnam
Montarop Yamabhai Thailand |
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