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Home > Field of Cooperation > Health Research > Gut leak and microbiome contributions to severe dengue disease
Gut leak and microbiome contributions to severe dengue disease
Principal Investigator / Affiliation Katryn Stacey (Professor) / The University of Queensland flag Australia Australia
Asada Leelahavanichkul (Associate Professor) / Chulalongkorn University flag Thailand Thailand
Dieter Tourlousse (Senior scientist) / National Institute of Advanced Industrial Science and Technology flag Japan Japan
Year Adopted 2022
Research Period 3 years
General Description of the Research Project This cooperative research project aims to establish the role of gut bacteria in the manifestations of severe dengue virus infection. Mosquito-borne dengue virus is a major health threat in the tropics, with severe disease involving life-threatening bleeding and shock. We propose that severe disease is the result of virus-induced damage to the gut, allowing bacterial products into the body. Collaborators in Thailand, Japan and Australia will investigate the impact of gut bacteria on dengue disease and possible live bacterial therapies
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Principal Investigator / Country of Research Team
Photo Katryn Stacey

Katryn Stacey

flag Australia
Photo Asada Leelahavanichkul

Asada Leelahavanichkul

flag Thailand
Photo Dieter Tourlousse

Dieter Tourlousse

flag Japan