Researchers
Name (Institute) |
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| Specialty | Clinical mycobacterilogy | ||||
| Science Interest (Past) |
I worked for the development of TB diagnostics for more than 25 years. The major objectives are to improve the specimen collection efficiency, specimen concentration techniques, nucleic acid amplification technology, and drug susceptibility testings. I also worked for drug resistance surveys in Japan and in other countries as a supra-national reference laboratory in WHO Western Pacific Region. | ||||
| Science Interest (Current) |
I am currently working still for the development of sensitive TB diagnostics mainly using nucleic acid amplification methods. The current topic is specimen concentration efficiency. We evaluated several different types of concentration techniques, including magnetic beads, dielectrophoresis, and so on. They have increased the current sensitivity of any nucleic amplification methods. In addition, our team is working for molecular epidemiological analysis of TB transmission and AMR diagnosis by genome sequencing. | ||||
| Science Interest (Future) |
I am much interested in the growth control of Mycobacterium tuberculosis. It is well known that growing tubercle bacilli contains semi-dormant bacillus group. The mechanisms are totally unclear, but if we can analyse the mechanism, it will be useful to prevent the development of TB disease from latent infection phase. | ||||
| Website / Contact | https://jata.or.jp/english/ https://www.facebook.com/satoshi.mitarai.5/ https://www.researchgate.net/profile/Satoshi_Mitarai |
